PRESTALIA combines two key hypertensive agents, perindopril arginine and amlodipine besylate, and is indicated for first-line treatment of hypertension. Lowering blood pressure may prevent heart attack, stroke, or death. PRESTALIA has been shown to reduce these events beyond simply lowering blood pressure.3 Both perindopril and calcium channel blockers (such as amlodipine) have been proven to reduce cardiac events and total mortality by 46%.3
Introducing PrestaliaDirect, a free program that helps you and your doctor manage your blood pressure while saving you time and money.
Do you have hypertension?
Most people with hypertension have no signs or symptoms, even if their blood pressure reaches dangerously high levels. That’s why testing and monitoring your blood pressure is so important. Awareness is the first step to treatment.
Seek immediate medical attention if you have any of the following symptoms: severe headaches, fatigue or confusion, vision problems, chest pain, difficulty breathing, irregular heartbeat, blood in your urine, or pounding in your chest, neck, or ears. You could be having a hypertensive crisis that could lead to heart attack or stroke.
- PRESTALIA (perindopril arginine and amlodipine) Tablets [package insert]. Durham, NC; Adhera Therapeutics, Inc. 2019.
- Prestalia Full Prescribing Information. https://prestalia-us.net/package-insert
- Bertrand ME, Ferrari R, Remme WJ, et al; EUROPA Investigators. Clinical synergy of perindopril and calcium-channel blocker in the prevention of cardiac events and mortality in patients with coronary artery disease. Post hoc analysis of the EUROPA study. Am Heart J. 2010;159(5):795-802.
- The Lancet Publishing Group: Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Angio-Scandinavian Cardiac Outcomes Trial–Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial. In: www.thelancet.com, Vol. 361, No. 9364, p1149-1158 [Internet]. 2003 Apr 5 – [cited 2016 Jun 15] Available from http:thelancet.com/journals/lancet/article/P1150140-6736(03)12948-0/abstract.